Hyperhidrosis : Causes for
is excessive sweating. Hyperhidrosis is defined as the production
of 100mg of sweat in the axilla over 5 minutes. The human body has
2-4 million eccrine sweat glands which function to cool the body
Innervations of these sweat glands are from the hypothalamic preoptic
sweat center in the brain through brainstem and medulla. These nerves
then enter the spinal cord and synapse in the anterolateral cell
column of the spinal cord. These neurons subsequently exit the spinal
cord and enter the sympathetic ganglia in the chest and finally
supply the upper limbs.
It is thought that the over stimulation
of the sweat glands in hyperhidrosis is related to the over activity
of the sympathetic nervous system. Perspiration or sweating can
be induced by emotional stress of thermal stimuli.
Emotional sweating is more common in the
hands, underarm and feet. Subsequently emotional sweating or perspiration
stops during sleep but thermal sweating can occur during sleep.
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